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Abstract #1878

Physiologically synchronized multi-module pulsed arterial spin labeled (SymPASL) MRI

Hung Phi Do1 and Krishna S Nayak2

1Physics and Astronomy, University of Southern California, Los Angeles, CA, United States, 2Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Physiologically synchronized multi-module pulsed arterial spin labeling (SymPASL) involves pulsed labeling that is applied several times prior to pulsations in the arterial blood supply. Simulations and in vivo measurements in human kidneys demonstrate that SymPASL provides superior SNR and SNR efficiency compared to conventional flow-sensitive alternating inversion recovery (FAIR) ASL with a single labeling pulse. Simulations suggest that SymPASL provides comparable SNR and SNR efficiency to pseudo-continuous ASL (PCASL), with lower specific absorption rate (SAR).

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