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Abstract #1917

Quantification of tracer kinetic and hemodynamic parameters of human breast tumor and fibro-glandular tissue using DCE-MRI data

Snekha Sehrawat1, Pradeep Kumar Gupta 2, Meenakshi Singhal2, Rakesh Kumar Gupta2, and Anup Singh1,3

1Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Delhi, India, 2Fortis Memorial Research Institute, Gurgaon, India, Delhi, India, 3Department for Biomedical Engineering, AIIMS Delhi, New Delhi, India.

Objective of current study was to develop a framework for computing tracer kinetic parameters using GTKM model and hemodynamic parameters using first pass analysis of human breast tissue for characterizing of breast lesion; and also differentiation of the histological grade II and III of breast cancer. A significant difference between benign, malignant and fibroglandular tissues; and also between grade II and III of breast cancer were observed.

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Abstract