This article is to explore the feasibility of liver fat quantification via dynamic liver enhancement scanning after injection of Gd-EOB-DTPA. IDEAL-IQ was used to quantify liver fat in 65 patients who were injected with contrast. IDEAL-IQ was performed four times to determine the fat fraction (FF) and R2*. One-way repeated-measures analysis was conducted to evaluate the difference between the four time points of the FF. The assessment of FF at four time points in liver, spleen and spine showed no significant differences. However, after injection of contrast agent, R2* was increased, and the IDEAL-IQ result was relatively stable.