Abstract #2167

Loss of lateral asymmetry in the brain of mouse models of autism

Jacob Ellegood¹, Benjamin C Darwin¹, Matthijs C Van Eede¹, Mark Henkelman^1,2, and Jason P Lerch^1,2

¹Hospital for Sick Children, Toronto, ON, Canada, ²Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

Examination of lateral asymmetry differences in mouse models related to Autism. Using 42 different mouselines as a representative sample of an autistic population, we show a loss of asymmetry in the mutant mice compared to wild-type that may be indicative of functional and/or behavioural variations.

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