Abstract #2220

Radiographic Atlas of Tumor Growth Pattern in Glioblastoma

Morteza Esmaeili¹, Anne Line Stensjøen¹, Erik Magnus Berntsen¹, Ole Solheim^1,2,3, and Ingerid Reinertsen^3,4

¹Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, NTNU, Trondheim, Norway, ²Department of Neurosurgery, St. Olav’s University Hospital, Trondheim, Norway, ³Norwegian National Advisory unit for Ultrasound and Image Guided Therapy, St. Olav’s University Hospital, Trondheim, Norway, ⁴Department of Medical Technology, SINTEF, Trondheim, Norway

In this study we assess the growth pattern of one of the most aggressive brain tumor in adults. Surgery is a standard of care for these patients, and understanding the prominent growth direction of tumor lesions can eventually benefit surgical planning. Contrast-enhanced MR data at two time-points of diagnosis and pre-operation were analyzed to derive mean 3D vector field demonstrating the growth directions. A DTI white matter (WM) atlas was used to investigate the degree of agreement and alignment of the generated vector field towards white matter fibers.

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