Autism spectrum disorders (ASD) are neurodevelopmental disorders that have been associated with disruptions in brain connectivity. Using resting-state fMRI, we assessed the variability of whole-brain connectivity in individuals with ASD. Using a variable, sliding-window technique to calculate the variance of dynamic functional connectivity (vDFC), we show increased vDFC in ASD as compared to typically developing controls among prefrontal regions and within the salience network. Measures of vDFC were significantly correlated with measures of social functioning among all subjects. This work is significant as it suggests increased neural noise and disorganization in ASD.