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Abstract #2292

Longitudinally consistent infant cortical surface atlases and parcellations from birth to 6 years of age

Zhengwang Wu1, Gang Li1, Yu Meng1, Li Wang1, Weili Lin1, and Dinggang Shen1

1BRIC, UNC-Chapel Hill, Chapel Hill, NC, United States

For the first time, a longitudinally consistent infant cortical surface atlas with densely-sampled 11 time points (at 1, 3, 6, 9, 12, 18, 24, 36, 48, 60, and 72 months of age) is built for better exploring the dynamic and critical early brain development, based on 339 serial MRI scans from 50 healthy infants. The longitudinal consistency and unbiasedness are ensured by an advanced two-stage group-wise surface registration during the atlas construction. To equip parcellations for our atlases, both the FreeSurfer parcellation (for coarse parcellation) and HCP MMP parcellation (for fine-grained parcellation) are mapped onto our infant atlases.

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