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Abstract #2308

MRI characteristics predicts clinical outcomes in severe hand, foot, and mouth disease´╝Üanalysis of 412 children in China

Zhouyang Lian1, Shuixing Zhang2, Kannie W.Y. Chan, and Guanshu Liu

1Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou, People's Republic of China, 2Guangdong Academy of Medical Sciences/Guangdong General Hospital, People's Republic of China

Most severe hand, foot, and mouth disease(HFMD) are caused by EV71 infections, which can result in central nervous system complications. So magnetic resonance imaging (MRI) acquisition is important for the patients with EV71 infection to reveal the location of lesions and select the potential severe cases with poor prognosis. We aim to reviewed MRI characteristics of the severe HFMD, using a multivariate approach to compare the prognosis of different lesion sites based on a large cohort with follow-up. Our findings suggested lesions located in medulla oblongata (P<0.015)and spinal cord(P<0.001) on MRI associated with poor prognosis.

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