Meeting Banner
Abstract #2331

Enhanced visualization of lesions in focal cortical dysplasia using the fluid and white-matter suppression (FLAWS) sequence

Xin Chen1, Tianyi Qian2, Tobias Kober3,4,5, Nan Chen1, and Kuncheng Li1

1Radiology, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China, 2MR Collaborations NE Asia, Siemens Healthcare, Beijing, People's Republic of China, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland, 4Radiology, University Hospital (CHUV), Lausanne, Switzerland, 5LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

High contrast in the lesion area is one of the most important prognostic factors for focal cortical dysplasia (FCD). The fluid and white-matter suppression (FLAWS) sequence provides two sets of 3D contrasts from one acquisition: one nulls the white-matter signal, the other nulls the cerebral spinal fluid signal. A new image (the FLAWS contrast) calculated from these two images may enhance the visualization of FCD lesion features, specifically the blurred grey-white matter interface and the transmantle sign. In this study, we assessed the ability of FLAWS to visualize FCD lesions. Our results demonstrate that FLAWS is sensitive to lesional tissue, especially the transmantle sign, providing additional value in MR-based FCD diagnostics.

This abstract and the presentation materials are available to members only; a login is required.

Join Here