Abstract #2432

Increased Anisotropy as Possible Compensatory Plasticity of Ventral Thalamic Nuclei to Gait Disturbance in Patients with Idiopathic Normal Pressure Hydrocephalus

Ping-Huei Tsai^1,2,3, Yung-Chieh Chen⁴, Shih-Wei Chiang^5,6, Hua-Shan Liu^3,7, Ming-Chung Chou⁸, Fei-Ting Hsu^2,3, Yu-Chieh Kao^1,3, Chia-Feng Lu^1,3, Hsiao-Wen Chung⁶, and Cheng-Yu Chen^1,2

¹Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ²Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, ³Translational Imaging Research Center, College of Medicine, Taipei Medical University, Taipei, Taiwan, ⁴1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ⁵Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, ⁶Graduate Institute of Biomedical Electrics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ⁷School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan, ⁸Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

This study allows improved localization of sensorimotor-related thalamic nuclei providing non-invasive evaluation of the microstructural changes of thalamus after iNPH, which may have a potential to contribute to early diagnosis and better prognosis prediction in the patients.

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