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Abstract #2439

A patch-based method for lesion in-painting in the spinal cord

Ferran Prados1,2, Manuel Jorge Cardoso1, Marios C Yiannakas2, Baris Kanber1,2, Hugh Kearney2, Claudia AM Gandini Wheeler-Kignshott2,3,4, and Sebastien Ourselin1

1Translational Imaging Group, CMIC, Dep. of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom, 2UCL Institute of Neurology, Queen Square MS Centre, University College London, London, United Kingdom, 3Department of Brain and Behavioural Sciences, University of Pavia, Italy, 4Brain MRI 3T Mondino Research Center, C. Mondino National Neurological Institute, Italy

Multiple Sclerosis lesions can impair most automated image-processing pipelines. They can be present with different sizes, contrasts and shapes and at multiple locations across the central nervous system. Whilst lesion-filling is often a required pre-processing step in the analysis of brain MR images, its potential utility in spinal cord imaging remains unexplored. This study introduces a method for in-painting lesions in the spinal cord and demonstrates its efficacy for improving the results of spinal cord MR image analysis.

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