Abstract #2540

Optimization of Neurite Orientation Density and Dispersion Imaging (NODDI) for In Situ Imaging

Ken Sakaie¹, Mark Lowe¹, and Daniel Ontaneda²

¹Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, ²Mellen Center for Multiple Sclerosis, The Cleveland Clinic, Cleveland, OH, United States

In situ imaging is a valuable context for validation of imaging measures against histology. This contribution describes optimization of diffusion MRI for NODDI in in situ imaging of a multiple sclerosis patient. The results are expected to facilitate validation of advanced diffusion MRI and other tissue microstructure meausrements.

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