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Abstract #2615

2D UTE-based MR thermometry of frozen tissue: feasibility during in vivo MRI-guided cryoablation

Christiaan G. Overduin1, Axel J. Krafft2, Michael Bock2, Hans JF Langenhuijsen3, Sjoerd F.M. Jenniskens1, Jurgen J. Fütterer1,4, and Tom W.J. Scheenen1

1Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, Netherlands, 2Radiology - Medical Physics, Medical Center University of Freiburg, Freiburg, Germany, 3Urology, Radboud University Medical Centre, Nijmegen, Netherlands, 4MIRA Institute for Biomedical Engineering and Technical Medicine, University of Twente, Enschede, Netherlands

This study assessed the feasibility of 2D UTE-based MR thermometry of frozen tissue during in vivo MRI-guided cryoablation. Axial 2D UTE images were acquired at the end of the first and second freeze cycle during an MRI-guided renal cryoablation procedure. Measurable MR signal could be obtained from frozen tissue. MR temperature maps were estimated using a relative signal level calibration performed in ex-vivo porcine muscle. Our work demonstrates the feasibility of 2D UTE-based MR thermometry of frozen tissue during in vivo MRI-guided cryoablation, which could be an important step towards clinical application of this technique.

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