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Abstract #2790

Accelerated multi-contrast high isotropic resolution 3D intracranial vessel wall MRI using a tailored k-space undersampling and partially parallel reconstruction strategy.

Niranjan Balu1, Zechen Zhou2, Thomas Hatsukami1, Mahmud Mossa-Basha1, and Chun Yuan1

1University of Washington, Seattle, WA, United States, 2Philips Healthcare, Beijing, People's Republic of China

Identification and differentiation of intracranial vessel wall pathologies requires multi-contrast high isotropic resolution 3D vessel wall MRI. However scan times for multi-contrast intracranial vessel wall imaging (IVWI) are too long to be tolerated by patients. We have developed a tailored k-space undersampling and partially parallel reconstruction strategy to accelerate 0.5mm 3D isotropic multi-contrast IVWI sequences to five minutes each. We demonstrate an accelerated multi-contrast IVWI protocol that provides similar vessel delineation as fully sampled sequences. Protocol performance was assessed in patients with intracranial atherosclerotic disease and showed clear delineation of vessel wall and atherosclerotic plaque.

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