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Abstract #2907

4D-T2 weighted MRI for lung radiotherapy treatment planning

Joshua N Freedman1,2, David J Collins1,2, Christopher M Rank3, Hannah Bainbridge1, Simeon Nill1, Marc Kachelrie├č3, Uwe Oelfke1, Martin O Leach1,2, and Andreas Wetscherek1

1Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom, 2CR-UK Cancer Imaging Centre, The Institute of Cancer Research, London, United Kingdom, 3Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Compared to 4D-CT, 4D-T2w MRI should better characterise respiratory motion in radiotherapy, due to its superior soft tissue contrast. However, 4D-T2w MRI is difficult to acquire due to the long echo and repetition time required. Here, 4D-T2w MRI is obtained by applying motion information from a 4D-T1w volume to a static 3D-T2w volume. For three patients, 4D-T2w MRI was compared to 4D-T1w MRI. Diaphragm positions were consistent to <1.5mm. A method to calculate 4D-T2w MRI, with potential application to an MR-linac, is presented and verified.

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