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Abstract #2915

Reproducibility of Quantitative DW-MRI and DCE-MRI of the Breast in the Community Setting: Preliminary Results

Anna G. Sorace1, Jack Virostko1, Stephanie L. Barnes2,3, Jeffrey Luci4, Debra Patt5, Boone Goodgame1,6, Sarah Avery7, and Thomas E. Yankeelov1,2,3

1Internal Medicine, University of Texas at Austin, Austin, TX, United States, 2Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, 3Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, United States, 4Neuroscience, University of Texas at Austin, Austin, TX, United States, 5US Oncology Network, Austin, TX, United States, 6Seton Medical Center, Austin, TX, United States, 7Austin Radiological Association, Austin, TX, United States

Implementation of quantitative DCE-MRI and DW-MRI in the community setting has the potential to impact patient care for a large number of breast cancer patients. Quantitative DW-MRI and DCE-MRI was assessed in phantoms and normal subjects across three sites. In normal subject fibroglandular tissue, the average percent difference in ADC across sites for all subjects was 1.8%, while the average percent difference in the inversion recovery scan and B1- corrected T1 map were 14% and 7.3%, respectively. Overall, the results from the phantom and normal subject scans reveal that quantitative MRI can be successfully implemented in the community setting.

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