In order to explore the changes of metabolites in the amygdala and the anterior cingulate of PTSD after earthquake, MR spectroscopy was applied. MRS showed higher ml and NAA levels in ACC, higher NAA levels in the right amygdala of PTSD group as compared to healthy controls. Besides, both in PTSD and healthy controls, NAA+NAAG levels were higher in the left amygdala than the right. And our results indicate there are some metabolic changes in amygdala and ACC of PTSD subjects. Whether combining depressive disorders, cause of PTSD and types of traumatic causes may have contributed to the inconsistency.