Electron paramagnetic resonance (EPR) imaging is a noninvasive imaging method for visualizing the brain redox status using nitroxide compounds as imaging probes. A digital imaging system for three-dimensional continuous-wave EPR imaging of small animals was developed using a high-speed analog-to-digital converter, digital-to-analog converters and field programmable gate array integrated circuits to improve the signal-to-noise ratio (SNR) and visualize the precise brain redox status in mice. Compared to an analog EPR imager, the digital EPR imager obtains a higher SNR of a phantom and produces images with sufficient quality to create a more accurate brain redox map of the mouse head.
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