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Abstract #3199

Water-fat separated T1 mapping in the liver and correlation to hepatic fat fraction

Claudia Fellner1, Philipp Wiggermann1, Dominik Nickel2, Niklas Verloh1, Stephan Kannengießer2, Christian Stroszczynski1, and Michael Haimerl1

1Institute of Radiology, University Hospital Regensburg, Regensburg, Germany, 2MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany

Fat signal fraction (FF) and R2* mapping as well as MRS of the liver were performed in 201 patients. Results for FF from imaging and MRS were compared to a newly defined parameter T1_FF. T1_FF was calculated from a variable flip angle 3D GRE technique with 2 echo times. Based on the Dixon method, T1 maps from in-phase and from water signal were calculated and T1_FF was deduced. T1_FF correlated well with FF and might be used as a novel estimation of fat fraction. Relevant discrepancies were seen in cases with high R2*.

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