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Abstract #3212

Fast self-gated 4D flow measurements in the murine aortic arch with retrospective radial sampling

Patrick Winter1, Kristina Andelovic2, Thomas Kampf1,3, Peter Jakob1,4, Wolfgang Bauer2, and Volker Herold1

1Experimentelle Physik V, Universität Würzburg, Würzburg, Germany, 2Medizinische Klinik und Poliklinik I des Universitätsklinikums Würzburg, Würzburg, Germany, 3Universitätsklinikum Würzburg, Institut für Diagnostische und Interventionelle Radiologie, Würzburg, Germany, 4Fraunhofer IIS, Fraunhofer EZRT, Magnetresonanz- und Röntgenbildgebung (MRB), Universität Würzburg, Würzburg, Germany

A self-navigated radial 4D-PC sequence is presented for accelerated ECG-free 4D flow measurements in the murine aortic arch. Self-navigation signals were extracted from the radial DC signal and used for retrospective motion synchronization. 3D-Cines with 30 frames were reconstructed with a spatial resolution of 100 µm. The volume flow was determined at 4 2D slices extracted from the 3D dataset and the 3D flow was visualized with streamlines. The results are in good accordance with results reported for ECG-triggered measurements. The new method yields high potential for preclinical studies of hemodynamics and can also be transferred to applications in humans.

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