Lymphatic interventions are increasingly performed for the treatment of chylous leakages. Pre-interventional evaluation of the central lymphatic system is important for adequate patient selection and planning of the interventional technique. We describe a new transpedal approach for MR-lymphangiography (tMRL) to evaluate the anatomy of central lymphatics including anatomical variations, as well as for detection of leakages and analysis of a potential interventional access site. Our results demonstrate that central lymphatic anatomy can be readily evaluated using tMRL in the majority of patients scheduled for lymphatic interventions. It is a well-tolerated, valuable diagnostic tool in the pre-interventional work-up of lymphatic interventions.