There is a global interest in healthy aging and also to avoid metabolic dysfunction. BAT and WAT play an important role in modulating the energy expenditure. In this study we have investigated the interscapular BAT and abdominal adipose tissues in young and old rats. During aging the iBAT activity is reduced due to the increase in “white” like adipocytes. The abdominal adipose tissues including VAT and SAT show increase in adipocyte size resulting in hypertrophy. Modulating these fat depots with nutritional interventions is of significant clinical interest.