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Abstract #3457

Quantitative evaluation of PROPELLER DWI using QIBA diffusion phantom

Joshua Yung1, Hua Ai1, Ho-Ling Liu1, and R Jason Stafford1

1Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States

The purpose of this study was to characterize ADC values when varying imaging parameters in a diffusion-weighted (DW) FSE sequence with Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction (PROPELLER) k-space trajectory. The QIBA diffusion phantom was used to quantitatively evaluate the different pulse sequences. The DW PROPELLER sequence showed good agreement with the QIBA SE EPI sequence with the ETL=20 and b-value of 0 and 2000 s/mm2 sequence having with a r2=0.9034. The DW PROPELLER sequence is promising for quantitative evaluation of ADC values and this study may help improve clinical protocols using diffusion weighted imaging.

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