Meeting Banner
Abstract #3476

Stability metrics for optic radiation tractography: towards damage prediction after resective surgery

Stephan Meesters1,2, Pauly Ossenblok2,3, Louis Wagner2, Olaf Schijns2,4, Paul Boon2, Luc Florack1, Anna Vilanova3,5, and Remco Duits1

1Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, Netherlands, 2Academic Center for Epileptology Kempenhaeghe & Maastricht UMC+, Heeze, Netherlands, 3Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 4Neurosurgery, Maastricht UMC+, Maastricht, Netherlands, 5Mathematics and Computer Science, Delft University of Technology, Delft, Netherlands

An accurate delineation of the optic radiation (OR) is useful in reducing the risk of a visual field deficit after temporal lobe resective surgery. However, tractography, especially of the probabilistic kind, is prone to generate spurious (false-positive) streamlines that are poorly aligned with the surrounding bundle. Fiber-to-bundle coherence measures are applied to identify and remove spurious fibers, which together with test-retest parameter estimation can provide a reconstruction of the OR that is robust to the stochastic realization of probabilistic tractography. Pre- and post-operative comparison of the OR is performed for epilepsy patients to quantify the accuracy of damage prediction.

This abstract and the presentation materials are available to members only; a login is required.

Join Here