It is necessary to correct for susceptibility artefacts in DW-MR, but there are a number of available strategies to choose from. In this work we apply a simulation framework, previously used to assess motion and eddy current correction strategies, to quantitatively evaluate methods for susceptibility correction. Our results indicate that methods that use reversed phase-encoding data perform the best. Furthermore they show that non-linear registration of diffusion data to a structural target in insufficient to fully correct for the susceptibility artefact.
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