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Abstract #3537

The Neonatal DTI fiber atlas for studies of brain development at birth

Rachel J Steiner1,2, Sarah J Short3, Rebecca Knickmeyer Santelli3, Audrey Rose Verde3, Aditya Gupta3, Fran├žois Budin4, Katherine A Gilmore3, Nagesh Adluru5, Guido Gerig6, John H Gilmore3, and Martin A Styner3,7

1Center for Investigating Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States, 2Psychology, University of Wisconsin-Madison, Madison, WI, United States, 3Psychiatry, University of North Carolina at Chapel Hill, 4Kitware Inc., 5Waisman Center, University of Wisconsin-Madison, 6Tandon School of Engineering, Department of Computer Science & Engineering, NYU, 7Department of Computer Science, University of North Carolina at Chapel Hill

Given the increasing popularity and wealth of DWI data in the field of neuroimaging, there is a critical need for the development of publically available resources that enable widespread application of a set of template fibers for atlas based along-tract analysis supporting an adequate and reliable analysis of DTI in newborns in both practice and in clinical research settings. To address this gap, we developed a Neonate DTI atlas that represents a typically developing human brain during the first few weeks of life. To the best of our knowledge, we are the first to develop a population atlas with this magnitude of quality and sample size, as well as with a comprehensive set of template fibers for semi-automatic tract based analysis. The DTI atlas and the tracts will be made available through NITRC.

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