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Abstract #3544

Feasibility of computed diffusion-weighted MR imaging for visualization of pancreatic adenocarcinoma: comparison with acquired diffusion-weighted imaging

Yoshihiko Fukukura1, Yuichi Kumagae1, Hiroto Hakamada1, Koji Takumi1, Kiyohisa Kamimura1, Masanoari Nakajo1, Tomoyuki Okuaki2, and Takashi Yoshiura1

1Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 2Philips Electronics Japan, TN, Japan

We compared directly acquired diffusion-weighted imaging (DWI) at b-values of 1500 s/mm2 and 2000 s/mm2 with computed DWI (cDWI) at the same b-values, which was calculated from directly acquired DWI data at b-values of 0 s/mm2 and 1000 s/mm2. Our main result is that the incidence of clear hyperintense pancreatic adenocarcinomas was significantly higher on cDWI at a b-value of 1500 s/mm2 than on directly acquired DWI at a b-value of 1000 s/mm2 (P < 0.001) and was comparable to the incidence on directly acquired DWI at a b-value of 1500 s/mm2, suggesting that cDWI to a b-value of 1500 s/mm2 has diagnostic merit.

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