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Abstract #3559

Assessment of Liver Function of HBV-induced Cirrhosis using T1 Mapping on Gd-EOB-DTPA-Enhanced MRI

Xueqin Zhang1, Jian Lu1, Tao Zhang1, Jifeng Jiang1, Ding Ding1, Sheng Du1, and Weibo Chen2

1Nantong Third People’s Hospital, Nantong University, Nantong, People's Republic of China, 2Philips Healthcare, Shanghai, People's Republic of China

The purpose of this study was to investigate the ability of T1 mapping on Gd-EOB-DTPA-enhanced MRI for the assessment of liver function of HBV-induced cirrhosis. We used Look-Locker sequences to acquire T1 mapping images pre and post-contrast at 5, 10, 15 and 20 minutes after Gd-EOB-DTPA administration, T1 relaxation times of the liver parenchyma were measured, reduction rates of T1 relaxation times between pre- and post-contrast enhancement were calculated, our study showed that Gd-EOB-DTPA-enhanced T1mapping MRI is useful for the evaluation of Liver function of HBV-induced cirrhosis.

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