Meeting Banner
Abstract #3627

Evaluation of 3D GRASE and 2D MB-EPI for Multi-Delay PCASL Imaging

Xiufeng Li1, Xingfeng Shao2, Dingxin Wang1,3, Sudhir Ramanna1, Steen Moeller1, Kamil Ugurbil1, Essa Yacoub1, and Danny J.J. Wang2

1Radiology-CMRR, University of Minnesota, Minneapolis, MN, United States, 2Laboratory of FMRI Technology, Stevens Neuroimaging and Informatics Institute, University of Southern California, CA, United States, 3Siemens Medical Solutions USA Inc., MN, United States

Recently 2D multi-band (MB) imaging has emerged as a promising alternative to 3D acquisitions for arterial spin labeling imaging. As part of the Human Connectome Project, we evaluated a segmented 3D GRASE and 2D MB-EPI for multi-delay PCASL imaging in terms of test-retest repeatability and CBF/ATT quantification. The results indicated that compared to 3D GRASE, 2D MB-EPI is less sensitive to subject motion, provided comparable but more reproducible ATT and CBF estimates, and suffered less from data loss. 2D MB-EPI appears promising for multi-delay PCASL imaging, especially with limited imaging time and where higher spatial resolution is of interest.

This abstract and the presentation materials are available to members only; a login is required.

Join Here