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Abstract #3629

Single shot high resolution 3D arterial spin labeling using 2D CAIPI and ESPIRiT reconstruction

Xingfeng Shao1 and Danny JJ Wang1

1Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States

We present a single-shot 3D GRASE pCASL technique, which reduces the data loss due to motion, using 2D CAIPI sampling strategy, and reconstruct the under-sampled data using ESPIRiT. Proposed sequence employs 4-fold acceleration and achieves whole brain volume with isotropic 3×3×3 mm3 resolution. This technique was successfully applied for high resolution multi-delay ASL imaging, and CBF, ATT and T1 map could be simultaneously calculated in 4 min 14 sec.

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