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Abstract #3660

Magnetic Properties of Skeletal Muscle at 7T

Benjamin Tendler1 and Richard Bowtell1

1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom

The magnetic properties of skeletal muscle tissue were examined in a phantom consisting of a piece of muscle tissue embedded in agar. Frequency perturbation maps were generated from phase maps measured at 7T, with the phantom oriented at 29 angles to the external magnetic field. Using a novel minimisation technique, susceptibility and chemical exchange properties of the muscle tissue were obtained simultaneously. From this it was determined that skeletal muscle is significantly more diamagnetic than agar; there is a small anisotropic susceptibility component and a large, orientation independent positive offset within the tissue, hypothesised to be due to chemical exchange.

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