Abstract #3674

# Coherence Enhancement in QSM via Anisotropic Weighting in Morphology-Enabled Dipole Inversion

Youngwook Kee1, Pascal Spincemaille1, Junghun Cho1,2, and Yi Wang1,2

1Weill Cornell Medical College, New York, NY, United States, 2Cornell University, Ithaca, NY, United States

The current regularization in morphology-enabled dipole inversion (MEDI) does not take into account orientation information in morphology between QSM and its corresponding magnitude image. In this abstract, we consider such orientation information to enhance structural coherence between the two images. In doing so, we achieve better image quality as well as higher RMSE (root mean square error) and HFEN (high frequency error norm) with respect to COSMOS and $$\chi_{33}$$\$.

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