We demonstrate for the first time abilities to perform lymphangiography non-invasively using turbo-spin-echo 3.0T MRI pulse sequences. Contrast consistent with lateralizing disease was observed in patients with known secondary lymphedema from breast cancer treatment-related lymphedema, which also adjusted in an expected manner following manipulation of lymphatic stasis through manual lymphatic drainage therapy. These findings suggest that MRI may be well-suited to evaluate lymphatic functioning and lymphedema treatment response, and may have relevance for informing personalized lymphedema risk before surgery or following breast cancer therapies.
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