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Abstract #3896

Fast Magnetic Resonance Fingerprinting of Mouse Brain Using a Spiral Trajectory

Yuning Gu1, Charlie Wang1, Christian Anderson1, Yuchi Liu1, Dan Ma1, Yun Jiang1, Mark A. Griswold1,2, Chris A. Flask1,2,3, and Xin Yu1,2,4

1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Department of Radiology, Case Western Reserve University, Cleveland, OH, United States, 3Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States, 4Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, United States

In this study we developed spiral-based MRF sequences for fast T1 and T2 mapping of mouse brain at 7T. A variable density spiral trajectory that fully sampled the inner 10×10 k-space with 4 interleaves enabled up to 6-fold acceleration for both MRF-bSSFP and MRF-FISP sequences, corresponding to a 3-min scan to acquire 1024 time frames for simultaneous T1 and T2 mapping.

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