Assessment of WM myelination is important to diagnose WM disorders in infants and children. We retrospectively evaluated 109 subjects (age of 6-48 months) using modified Cecilia Parazzini’s scoring method based on T2WI visual evaluation. A significantly positive correlation was found between age and total scores of WM myelination with non-linear correlation coefficient of 0.948 (p<0.01). TBSS results demonstrated WM myelination progressed rapidly during age of 6-20 months and relatively stable during age of 21-48 months. The modified scoring method was more applicable to assess the WM myelination in infant with age of 6-20 months.