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Abstract #4186

Active and passive fMRI for preoperative localization of motor function areas in brain tumor patients

Chen Niu1, Xiao Ling1, Pan Lin2, Kun Zhang3, Xin Liu4, Liping Guo1, Wenfei Li1, Hao Song2, Ming Zhang1, and Maode Wang5

1Department of Medical Imaging, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'An, People's Republic of China, 2Key Laboratory of Biomedical Information Engineering of Education Ministry, Institute of Biomedical Engineering, Xi’an Jiaotong University, 3Department of Electronics Engineering, Northwestern Polytechnical University, 4Technical University Munich, 5Department of neurosurgery, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'An, People's Republic of China

The aim of this study is to investigate whether there is consistency between active and passive movement in patients with brain tumors. Two motor tasks (active and passive hand movement) were applied to brain tumor patients. Our results demonstrate that there is no statistical difference of activation intensity between active hand movement and passive hand movement in patients with brain tumors. Our results suggest that passive movement fMRI provides a potential method for presurgical mapping in cases where patients are unable to comply with task instructions.

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