Our aim was to study the feasibility of quantitative RAFF, T1ρcw, T1ρadiab and T2ρadiab imaging for the first time in human gliomas and to assess their ability to differentiate gliomas with specific genetic profile. FLAIR lesion segmentation and histogram analysis from parametric maps were applied. Both IDH mutated and 1p19q codeleted gliomas demonstrated a tendency for lower relaxation values compared to IDH wild-type and 1p19q intact gliomas, respectively. Additionally, T2ρ, adiab significantly correlated to Ki-67 and tumor aggressiveness. We conclude that RAFF, T1ρcw, T1ρadiab and T2ρadiab imaging of gliomas is feasible and carry a potential for improving non-invasive glioma characterization.