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Abstract #4245

High resolution 7 T magnetic resonance spectroscopic imaging of glioma in the brain

Gilbert Hangel1, Eva Heckova1, Bernhard Strasser1, Michal Pova┼żan1,2, Stephan Gruber1, Elisabeth Springer1, Georg Widhalm3, Matthias Preusser4, Siegfried Trattnig1,2, and Wolfgang Bogner1,2

1High Field MR Centre, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Department of Neurosurgery, Medical University of Vienna, 4Department of Medicine I, Division of Oncology, Medical University of Vienna

We present the application of single-slice high-resolution FID-MRSI with short acquisition delay at 7T that provides whole-slice metabolite maps in eight patients with different types of glioma. With six minutes measurement time, it could be easily integrated into a standard imaging protocol. The results show that it is possible to resolve metabolic deviations in an extended number of biochemical compounds in tumors with unprecedented spatial details, thereby offering deeper insight into the neurochemical profiles of different glioma types. This suggests that the demonstrated method has a high potential for the research of glioma.

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