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Abstract #4616

Identifying Perfusion Deficit Patterns in Unilateral Middle Cerebral Artery Stenosis Patients using Multi-Inversion Time Arterial Spin Labeling

Shuang Yan1, Tianyi Qian2, Li Zhang3, Josef Pfeuffer4, Mingli Li1, Bin Peng3, and Zhengyu Jin1

1Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China, Beijing, People's Republic of China, 2Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, 3Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China, Beijing, People's Republic of China, 4Siemens Healthcare, ApplicationDevelopment, Erlangen, Germany

To investigate the perfusion pattern in patients with unilateral middle cerebral artery stenosis, a multi-inversion time pulsed arterial spin labeling technique was used to measure the cerebral blood flow and bolus arrival time (BAT). The preliminary results indicatethat patients with cerebral infarction (CI) had longer BAT than patients with transient ischemic attack (TIA). Assuming CBF valuesare corrected in the areas with BAT longer than 1300ms and combine the corrected CBF with the BAT, we can distinguish TIA and CI cases from their perfusion deficits patterns.

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