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Abstract #4623

Magnetic particle imaging - The future of acute stroke imaging and treatment?

Peter Ludewig1, Nadine Gdaniec2, Jan Sedlacik3, Kannan M. Krishnan4, Christian Gerloff1, Tobias Knopp2, and Tim Magnus1

1Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 2Institute of Biomedical Imaging, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 3Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 4Materials Science and Engineering Department, University of Washington, Seattle, United States

Magnetic particle imaging (MPI) is a new tomographic imaging modality with superior temporal and spatial resolution compared to other imaging techniques, allowing 3D real-time assessment of vasculature and perfusion without X-rays or nephrotoxic contrast agents. For the first time we show that MPI can used for the diagnosis of acute pathologies like ischemic stroke by showing the first MPI stroke images in a murine stroke model. Additionally, we give an outlook how MPI may revolutionize not only stroke imaging but also stroke treatment, as the magnetic fields of the MPI can be used for catheter guidance and targeted drug delivery.

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