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Abstract #4714

Accelerated Time Resolved Phase Contrast Cerebral MRA to Evaluate Pulse Wave Velocity

Tzu Cheng Chao1,2, Yu-Chia Cheng3, Wen-Chau Wu4,5, Hsu-Hsia Peng6, Tzu-Chao Chuang7, Hsiao-Wen Chung5,8, Teng-Yi Huang9, and Yi-Jui Liu3

1Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan, 2Institute of Medical Informatics, National Cheng Kung University, Tainan, Taiwan, 3Department of Automatic Control Engineering, Feng-Chia University, Taichung, Taiwan, 4Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan, 5Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 6Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 7Department of Electrical Engineering, National Sun Yat Sen University, Kaohsiung, Taiwan, 8Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, 9Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

Time-resolved PCMRI has been applied to measure pulse wave velocity (PWV) for the assessment of aortic stiffness. However, longer scan time hinders its practice to achieve a high spatial and temporal resolution scan, especially required for the arteries inside of the head and neck. In the present work, an accelerated Time-resolved PCMRA was implemented to shorten scan time. The reconstruction combines temporal strategy and self-reference information to retain reasonable imaging quality. The results suggest that the proposed method differentiate PWV delay time from Common-Carotid artery to Middle-Cerebral arteries via Internal-Carotid artery with good quality within a 10-minute scan.

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