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Abstract #4760

SUPER-RESOLUTION RECONSTRUCTION OF LATE GADOLINIUM ENHANCEMENT CARDIOVASCULAR MAGNETIC RESONANCE IMAGES USING A RESIDUAL CONVOLUTIONAL NEURAL NETWORK

Archontis Giannakidis1,2, Ozan Oktay3, Jennifer Keegan1,2, Veronica Spadotto1,4, Inga Voges1, Gillian Smith1, Iain Pierce1, Wenjia Bai3, Daniel Rueckert3, Sabine Ernst1, Michael A Gatzoulis1, Dudley J Pennell1,2, Sonya Babu-Narayan1, and David N Firmin1,2

1NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom, 2National Heart & Lung Institute, Imperial College London, London, United Kingdom, 3Biomedical Image Analysis Group, Imperial College London, London, United Kingdom, 4Department of Cardiac, Thoracic and Vascular Sciences, University of Padua

Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) has enabled the accurate myocardial tissue characterization. Due to practical considerations, the acquisition of anisotropic two-dimensional (2D) stack volumes, with low through-plane resolution, still prevails in the clinical routine. We propose a deep learning-based method for reconstructing a super-resolved three-dimensional LGE-CMR data-set from a low resolution 2D short-axis stack volume. The method directly learns the residuals between the high and low resolution images. Results on clinical data-sets show that the proposed technique outperforms the state-of-the-art with regard to image quality. The fast speed of our model furthers facilitates its adoption for practical usage.

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