Meeting Banner
Abstract #4797

Modified Dispersion Model in Prostate Dynamic Contrast-Enhanced MRI

Kyunghyun Sung1, Xinran Zhong2, and Holden Wu2

1Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2Radiology, University of California, Los Angeles, Los Angeles, CA, United States

The dispersion imaging has shown great promise in prostate DCE-MRI, but there still exist practical limitations due to the complex model fitting. We describe a modified dispersion model to overcome these limitations by adapting a simple dispersion factor into the existing population-averaged arterial input function. We use the regions of interest, derived from the histological analysis, to evaluate both the quality of the model fitting and the ability of DCE-MRI parameters to delineate between cancerous and normal prostate tissues using 25 prostate patient cases available with the whole-mount histopathology.

This abstract and the presentation materials are available to members only; a login is required.

Join Here