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Abstract #4895

Comparison of the Capability for Quantitative Distinguishing Malignant from Benign Pulmonary Nodules among Dynamic First-Pass CE-Perfusion ADCT and MRI and FDG-PET/CT

Yoshiharu Ohno1,2, Yuji Kishida3, Sinichiro Seki1,2, Shigeharu Ohyu4, Masao Yui4, Wakiko Tani5, Noriyuki Negi5, Katsusuke Kyotani5, and Takeshi Yoshikawa1,2

1Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Advanced Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, Kobe, Japan, 3Division of Radiology, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 4Center for Medical Research and Development, Toshiba Medical Systems Corporation, Otawara, Japan, 5Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Japan

Quantification of perfusion parameter from dynamic CE-perfusion MRI at 3T system may be more difficult than that at 1.5T system, and contrast media concentration may have larger influence to measurement error of perfusion parameter on a 3T system. We hypothesized that a bolus injection protocol with appropriately small contrast media volume can provide accurate pulmonary perfusion parameter on dynamic CE-perfusion MRI at a 3T system. The purpose of this study was to determine the appropriate contrast media volume for quantitative assessment of dynamic CE-pulmonary MRI, when compared with dynamic CE-area-detector CT (ADCT) for quantitative evaluation of perfusion within whole lung.

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