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Abstract #4987

Measuring T1 and T2 of the small bowel wall at 3T

Hannah Grace Williams1,2, Penny A Gowland1, Luca Marciani2, Robert Scott3, Guruprasad Aithal2,3, and Caroline L Hoad1,3

1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom, 3NIHR Biomedical Research Unit in Gastrointestinal and Liver Diseases, Nottingham University Hospital, Nottingham, United Kingdom

Available techniques to measure in-vivo bowel permeability are inadequate for stratifying patients to identify those at risk of complications from increased bowel permeability. T1 and T2 measurements could potentially be indicators of changes in bowel wall structure and thus permeability. We have measured the T1 and T2 of the bowel wall to be 1.68±0.57 s and 0.08 ±0.02 s respectively. We found significant variations between and within subjects. However it is currently unknown whether some of these variations are real and some due to errors in the measurement process.

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