Meeting Banner
Abstract #5006

Crossing muscle fibres in the tongue resolved using constrained spherical deconvolution

Luuk Voskuilen1,2,3, Valentina Mazzoli2,4,5, Jos Oudeman2, Ludi E. Smeele1,6, Alfons J.M. Balm1,6, Ferdi van der Heijden1,7, Martijn Froeling8, Gustav J. Strijkers9, and Aart J. Nederveen2

1Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands, 2Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 3Department of Oral and Maxillofacial Surgery, Academic Centre for Dentistry Amsterdam and Academic Medical Center, University of Amsterdam and VU University Amsterdam, Amsterdam, Netherlands, 4Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, 5Orthopaedic Research Lab, Radboud UMCN, Nijmegen, Netherlands, 6Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam, Netherlands, 7Department of Robotics and Mechatronics, MIRA Institute, University of Twente, Enschede, Netherlands, 8Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 9Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

Tongue muscle architecture is suspected to be important in the prediction of speech and swallowing complications after surgery. The tongue contains areas of crossing muscle fibres unable to be resolved by diffusion tensor imaging (DTI). We show that constrained spherical deconvolution (CSD) is able to distinguish these crossing fibres ex vivo and in vivo using a clinically acceptable scan time of 10 min. Also, we show improved tractography in CSD compared to DTI, allowing segmentation of different tongue muscles which conforms to known anatomy.

This abstract and the presentation materials are available to members only; a login is required.

Join Here