Abstract #5011

T2-weighted Dixon TSE for accelerated simultaneous grading of whole body skeletal muscle fat infiltration and edema in patients with neuromuscular diseases

Sarah Schlaeger¹, Elisabeth Klupp¹, Dominik Weidlich², Barbara Cervantes², Marcus Deschauer³, Benedikt Schoser⁴, Sarah Bublitz³, Federica Montagnese⁴, Christoph Katemann⁵, Hendrik Kooijman⁵, Ernst J. Rummeny², Claus Zimmer¹, Jan S. Kirschke¹, and Dimitrios C. Karampinos²

¹Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, Munich, Germany, ²Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, ³Department of Neurology, Technical University of Munich, Munich, Germany, ⁴Friedrich-Baur-Institut, Ludwig-Maximilians-University, Munich, Germany, ⁵Philips Healthcare, Hamburg, Germany

The assessment of fatty infiltration and edema in the whole body musculature of patients with neuromuscular diseases typically requires the separate performance of a T₁-weighted sequence and a fat suppressed T₂-weighted sequence. T₂-weighted Dixon TSE enables the generation of T₂-weighted fat-separated and water-separated images, which could be used to simultaneously assess fatty infiltration and edema and to reduce total scan time. The present study examines the diagnostic performance of whole body T₂-weigthed Dixon TSE imaging in 10 patients with neuromuscular diseases.

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