Abstract #5211

Gradient Moment Dependent T2 Accuracy in FISP Magnetic Resonance Fingerprinting (MRF) at 7T

Christian Anderson¹, Charlie Wang¹, Yuning Gu¹, Yun Jiang¹, Dan Ma², Mark Griswold^1,2, Xin Yu^1,2,3, and Chris Flask^1,2,4

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, ³Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, United States, ⁴Pediatrics, University Hospitals Cleveland Medical Center, Cleveland, OH, United States

Magnetic Resonance Fingerprinting allows for rapid, simultaneous multi-parametric quantification. The use of a FISP imaging kernel is necessary due to field inhomogeneity in human body and preclinical imaging. We have observed that increases in the applied gradient moment lead to gradient moment size dependent changes in T2 accuracy. By examining different applied gradient moments we illustrate this loss of T2 accuracy while T1 measurement accuracy is maintained. This has implications for FISP MRF design and the implementation of unbalanced gradient moments for quantification.

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