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Abstract #5215

High resolution PET insert for high field preclinical MRI: evaluation of single ring system using 7T field strength

Willy Gsell1, Uwe Himmelreich1, Cindy Casteels2, Christophe M. Deroose2, Antonio J. Gonzalez3, Albert Aguilar3, Carlos Correcher4, Emilio Gimenez4, Cesar Molinos4, Ramiro Polo4, Thorsten Greeb5, Ralph Wissmann5, Sven Junge5, and Jose M. Benlloch3

1Biomedical MRI, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium, 2Nuclear Medicine, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium, 3i3M, Valencia, Spain, 4Oncovision, Valencia, Spain, 5Bruker Biospin, Ettlingen, Germany

We designed a novel PET insert based on monolithic LYSO crystals. From our first evaluation, we can conclude that sub-millimeter detector spatial resolution, combined with accurate photon DOI determination, make it possible to acquire high resolution reconstructed images. This enables us now to combine simultaneously high resolution and sensitivity PET with high field preclinical MRI to extract simultaneously complex data from anatomical to molecular information and to dynamically follow non-invasively animal models of different pathologies with no compromise in performance of each imaging modality.

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