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Abstract #5260

Simultaneous assessment of total CBV, aCBV and BOLD measures at 7 Tesla in motor and somatosensory cortices

Rosa M Sanchez Panchuelo1, Robert Turner1,2,3, and Susan Francis1

1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 3University of Amsterdam, Amsterdam, Netherlands

We combined Arterial Spin Labelling (ASL) and Vascular Space Occupancy (VASO) techniques into a double acquisition FAIR sequence with double echo readout to provide simultaneous measures of arterial Cerebral Blood Volume (aCBV), total CBV and BOLD signals. Using this technique at 7T, we successfully detected aCBV and total CBV (and BOLD) changes induced by both a motor task and a vibrotactile sensory stimulation paradigm, and show that activation maps derived with the independent ASL and VASO techniques largely overlap.

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